About Us

Dr. Wayne Klohs, PhD

Head of Clinical Design & Oncology Strategy

  • 40+ years of expertise in oncology drug discovery and development

  • Key contributor to the development and commercialization of breakthrough oncology products such as Tarceva®, Xtandi® and Nipent®

  • Former Senior Vice President and Global Therapeutic Area Head for Oncology at Astellas, Senior Director at Takeda and Head of Oncology (Ann Arbor) at Pfizer

A picture of Dr. Wayne Klohs, member of the Peptinovo team

Dr. Wayne D. Klohs, Ph.D. brings over 40 years of extensive experience in the pharmaceutical industry, with a focus on oncology drug discovery and development. He has held senior leadership positions across several major pharmaceutical companies, including Astellas Pharma, Pfizer, and Takeda Pharmaceuticals, where he played a pivotal role in advancing key oncology products such as Tarceva® and Xtandi®.

Dr. Klohs began his career in academic research, serving as an Assistant Professor at SUNY Buffalo before transitioning to the pharmaceutical industry at Parke-Davis/Warner-Lambert, where he led efforts in oncology drug discovery. Over the years, he has contributed to the successful development of multiple investigational drugs, including pentostatin (Nipent®) and other oncology therapies, through his expertise in both early-stage discovery and late-stage development.

In his most recent corporate role as Senior Vice President and Global Therapeutic Area Head for Oncology at Astellas Pharma, Dr. Klohs was instrumental in transforming the company’s oncology pipeline and driving successful new drug applications (NDAs) and marketing authorization applications (MAAs) for key cancer therapies. His leadership facilitated the growth of Astellas’ oncology division into a global business with a robust portfolio of marketed products.

As a biotech entrepreneur, Dr. Klohs served as President and CEO of Pi Squared Therapeutics, a start-up focused on targeting oncogenic protein stability, further showcasing his dedication to innovative cancer treatment solutions. Today, he continues to offer his wealth of knowledge as a consultant and advisor to numerous biotech firms, guiding the next generation of oncology drug development.

Dr. Klohs holds a Ph.D. from Indiana State University and completed postdoctoral training at Roswell Park Cancer Institute. His prolific career includes numerous publications, patents, and contributions to advancing cancer therapy through both scientific research and strategic development.